[Misc] Weight loss jabs - Mounjaro, Wegovy etc.

[Professor Plum]

Update, just onto my third jab, so 3 weeks in, weighed myself and now lost 12lb
Appetite much much lower, been up since 2.30 this morning to drop my daughter to Heathrow and I’ve just made myself eat something……possibly the longest I’ve ever gone without food

Good for you. Did you find that food noise/suppression kicked in immediately or did it take a few days? I know it varies from one person to the next so it’s of no great significance but am just curious. I’ll be starting today or tomorrow.

 

[wehatepalace]

Good for you. Did you find that food noise/suppression kicked in immediately or did it take a few days? I know it varies from one person to the next so it’s of no great significance but am just curious. I’ll be starting today or tomorrow.

Very quickly, and I’m finding it increases with each injection too

 

[Titanic]

Would I get the same results if I could summon up the willpower to eat a lot less... or do these jabs somehow accelerate weight loss?

 

[Professor Plum]

Would I get the same results if I could summon up the willpower to eat a lot less... or do these jabs somehow accelerate weight loss?

Yes, you’d get the same results if you ate a lot less. If you find that easy to do over a long period, that’s the way to go.

 

[Harry Wilson's tackle]

Would I get the same results if I could summon up the willpower to eat a lot less... or do these jabs somehow accelerate weight loss?

Yes.

No.

 

[Harry Wilson's tackle]

Yes, you’d get the same results if you ate a lot less. If you find that easy to do over a long period, that’s the way to go.

I have found the only way I can lose weight is via anxiety (which is something that affects me greatly).

I have found that when I don't drink booze (several days a week - which is admittedly a relatively new thing) I put on weight (I weigh myself daily - a neurodiversity thing), presumably because I snack more, and drink liters of fruit juice.

I've been off the ciggies fully (was largely fully) for quite a while now, and packing that in triggered a weight gain.

The weight has been steady, perhaps down a couple of kilos, for about 4 years. But stress and anxiety are a massive problem, I have come to realize (once my chronic gut issues were identified as not due to a gut problem but more likely to anxiety).

Sometimes you just can't win.

 

[Half Time Pies]

What happens after you have finished the injections and have lost the weight? How do people keep the weight off?

I have tried many diets over the years, the last time it was the fast 800 and I lost 2 stone in 12 weeks. After I finished I felt great and everyone was giving me compliments, I was full of praise about the fast 800 and recommended it to friends. This is the problem with diets, many of the extreme ones do work well and people are doing them when their motivation levels are high and they don't mind spending the money, willpower and time on them if its only going to be for a short period of time. They tell everyone they know how much they have lost and put pictures all over social media. What people don't see is what happens to them over the next 6/8/12 months and if they put the weight back on!

For me after the diet finished all the old habits came back , I developed a hernia so couldn't exercise and before I knew it I had put all they weight back on and bit more for good measure! In my opinion if you can't eat healthy and exercise before you try an extreme diet, is very unlikely that you will be able to do it after you have finished the diet.

 

[Weststander]

I have found the only way I can lose weight is via anxiety (which is something that affects me greatly).

I have found that when I don't drink booze (several days a week - which is admittedly a relatively new thing) I put on weight (I weigh myself daily - a neurodiversity thing), presumably because I snack more, and drink liters of fruit juice.

I've been off the ciggies fully (was largely fully) for quite a while now, and packing that in triggered a weight gain.

The weight has been steady, perhaps down a couple of kilos, for about 4 years. But stress and anxiety are a massive problem, I have come to realize (once my chronic gut issues were identified as not due to a gut problem but more likely to anxiety).

Sometimes you just can't win.

We all have our vices.

I suppose, minimise it to those which do least damage, meaning you’re be around for your loved ones for much longer.

Well done for packing in the cigarettes, literally a killer, I lost family in their 50’s to the f@ckers.

 

[Professor Plum]

I have found the only way I can lose weight is via anxiety (which is something that affects me greatly).

I have found that when I don't drink booze (several days a week - which is admittedly a relatively new thing) I put on weight (I weigh myself daily - a neurodiversity thing), presumably because I snack more, and drink liters of fruit juice.

I've been off the ciggies fully (was largely fully) for quite a while now, and packing that in triggered a weight gain.

The weight has been steady, perhaps down a couple of kilos, for about 4 years. But stress and anxiety are a massive problem, I have come to realize (once my chronic gut issues were identified as not due to a gut problem but more likely to anxiety).

Sometimes you just can't win.

My weight problems started in 1995 when I stopped smoking. I put on about 3 stone over a couple of years and have never really got back to where I was. Don’t take that as suggesting that must happen to everyone. It’s not uncommon to put on weight after giving up but plenty of people manage to get it off again.

I’ve tried every diet under the sun. They work for a while but I struggle to maintain them. Keto/low carb has always been successful in the short term (ie up to 3 or 4 months) but it’s very hard to avoid bread, pasta, rice, potatoes etc indefinitely.

Hence this current Mounjaro plan. Something that allows me eat relatively normally but prevents overeating sounds ideal in theory though @Half Time Pies asks the $64,000 question — what happens at the end of the programme? Do you have to just keep taking it or has your body learnt a permanent lesson en route to the destination (presuming that’s reached).

This is something I will shortly find out.

But anyway, good luck all. We are all fighting our unique and often lonely battles.

 

[Professor Plum]

We all have our vices.

I suppose, minimise it to those which do least damage, meaning you’re be around for your loved ones for much longer.

Well done for packing in the cigarettes, literally a killer, I lost family in their 50’s to the f@ckers.

Stopping smoking was possibly the best thing I’ve ever done, regardless of the weight issues it triggered.

 

[SkirlieWirlie]

What happens after you have finished the injections and have lost the weight? How do people keep the weight off?

I have tried many diets over the years, the last time it was the fast 800 and I lost 2 stone in 12 weeks. After I finished I felt great and everyone was giving me compliments, I was full of praise about the fast 800 and recommended it to friends. This is the problem with diets, many of the extreme ones do work well and people are doing them when their motivation levels are high and they don't mind spending the money, willpower and time on them if its only going to be for a short period of time. They tell everyone they know how much they have lost and put pictures all over social media. What people don't see is what happens to them over the next 6/8/12 months and if they put the weight back on!

For me after the diet finished all the old habits came back , I developed a hernia so couldn't exercise and before I knew it I had put all they weight back on and bit more for good measure! In my opinion if you can't eat healthy and exercise before you try an extreme diet, is very unlikely that you will be able to do it after you have finished the diet.

The book I mentioned in post #52 talks to this in detail. The Dr who wrote the book has been treating patients for obesity through surgical procedures for many years and a very high level summary of his view is that in effect starving your body for weeks or months will result in a physical rebound when you start to reintroduce foods that you've excluded during that time and in fact your body will go into the reverse of 'starvation mode' to restock it's fat reserves. I think this is where some of his observations and theories come in rather than 100% study based.

But, I think the key is about reducing calorie intake, eating healthy foods (this includes fats, as well as protein and carbohydrates), which will stabilise blood sugars, reduced spikes, etc so when you start to increase your intake once you've hit the weight you're aiming for, it minimises any negative rebound.

It's about making permanent lifestyle changes , not short term fad diets to lose weight as quickly as possible. Slow reductions over time much more sustainable and I suspect better for your overall body and health too.

Edit: I find this subject fascinating and wish it had been a thing when I was about to leave secondary school that I could have chosen as a career. A lot of the nutritional advice disseminated by governments worldwide for over 50 years is based on 'scientific studies' paid for by sugar companies in the 50's demonising fat to deflect from the damage done by their product.

My diet now is much higher in fat than it used to be, but good fats (olive oil, nuts, seeds, oily fish, etc) but good for health and reducing hunger too.

 

[cloud]

Update, just onto my third jab, so 3 weeks in, weighed myself and now lost 12lb
Appetite much much lower, been up since 2.30 this morning to drop my daughter to Heathrow and I’ve just made myself eat something……possibly the longest I’ve ever gone without food

It could be that going without food that has helped with the weight loss.

For anyone wanting to lose weight without drugs, a combination of 1) intermittent fasting (e.g. eat within a 10 hour window each day), 2) eating 30g fibre a day, and 3) max 1250 calories per day will result in healthy and fairly fast weight loss.

Eating 30g fibre per day will make you feel full and suppress your appetite by increasing levels of GLP-1 (glucagen-like peptide), which is effectively what the weight loss drugs do. A high fibre diet will also reduce glucose spikes and inflammation, which is better for both mental and physical health.

Finally, making your first meal of the day savoury rather than sweet will reduce food cravings during the day.

 

[Titanic]

It could be that going without food that has helped with the weight loss.

For anyone wanting to lose weight without drugs, a combination of 1) intermittent fasting (e.g. eat within a 10 hour window each day), 2) eating 30g fibre a day, and 3) max 1250 calories per day will result in healthy and fairly fast weight loss.

Eating 30g fibre per day will make you feel full and suppress your appetite by increasing levels of GLP-1 (glucagen-like peptide), which is effectively what the weight loss drugs do. A high fibre diet will also reduce glucose spikes and inflammation, which is better for both mental and physical health.

Finally, making your first meal of the day savoury rather than sweet will reduce food cravings during the day.

Salty porridge it is then

 

[jordanseagull]

It could be that going without food that has helped with the weight loss.

For anyone wanting to lose weight without drugs, a combination of 1) intermittent fasting (e.g. eat within a 10 hour window each day), 2) eating 30g fibre a day, and 3) max 1250 calories per day will result in healthy and fairly fast weight loss.

Eating 30g fibre per day will make you feel full and suppress your appetite by increasing levels of GLP-1 (glucagen-like peptide), which is effectively what the weight loss drugs do. A high fibre diet will also reduce glucose spikes and inflammation, which is better for both mental and physical health.

Finally, making your first meal of the day savoury rather than sweet will reduce food cravings during the day.

This is absolutely spot on. All other extreme weight loss programmes/pharmaceutical interventions simply do not work in the long term. The extreme weight loss in the first month is also almost exclusively fluid-based - the fat isn’t just magically disintegrating.

When as a society we are eating so much - and so much ultra processed non-foods - food that we need injections to suppress appetite, I think we have a bloody serious problem. That said I wish everyone on a weight loss journey the best. But sustainability is the key.

 

[Thunder Bolt]

Salty porridge it is then

Scrambled eggs (without toast) good protein

 

[Thunder Bolt]

What happens after you have finished the injections and have lost the weight? How do people keep the weight off?

I have tried many diets over the years, the last time it was the fast 800 and I lost 2 stone in 12 weeks. After I finished I felt great and everyone was giving me compliments, I was full of praise about the fast 800 and recommended it to friends. This is the problem with diets, many of the extreme ones do work well and people are doing them when their motivation levels are high and they don't mind spending the money, willpower and time on them if its only going to be for a short period of time. They tell everyone they know how much they have lost and put pictures all over social media. What people don't see is what happens to them over the next 6/8/12 months and if they put the weight back on!

For me after the diet finished all the old habits came back , I developed a hernia so couldn't exercise and before I knew it I had put all they weight back on and bit more for good measure! In my opinion if you can't eat healthy and exercise before you try an extreme diet, is very unlikely that you will be able to do it after you have finished the diet.

Many people on the 800 diet, having lost the weight, switch to the 5/2 plan, where you eat relatively normally for five days, but two days a week (of your choice) stick to 800 calories.

 

[Half Time Pies]

The book I mentioned in post #52 talks to this in detail. The Dr who wrote the book has been treating patients for obesity through surgical procedures for many years and a very high level summary of his view is that in effect starving your body for weeks or months will result in a physical rebound when you start to reintroduce foods that you've excluded during that time and in fact your body will go into the reverse of 'starvation mode' to restock it's fat reserves. I think this is where some of his observations and theories come in rather than 100% study based.

But, I think the key is about reducing calorie intake, eating healthy foods (this includes fats, as well as protein and carbohydrates), which will stabilise blood sugars, reduced spikes, etc so when you start to increase your intake once you've hit the weight you're aiming for, it minimises any negative rebound.

It's about making permanent lifestyle changes , not short term fad diets to lose weight as quickly as possible. Slow reductions over time much more sustainable and I suspect better for your overall body and health too.

Edit: I find this subject fascinating and wish it had been a thing when I was about to leave secondary school that I could have chosen as a career. A lot of the nutritional advice disseminated by governments worldwide for over 50 years is based on 'scientific studies' paid for by sugar companies in the 50's demonising fat to deflect from the damage done by their product.

My diet now is much higher in fat than it used to be, but good fats (olive oil, nuts, seeds, oily fish, etc) but good for health and reducing hunger too.

I didn't have time to read the whole thread so I missed that. For me the biggest problem is that a lot of the diet industry ignores the fact that for many people there is an emotional element to overeating and for some this can even develop in to a addiction as powerful and difficult to overcome as alcohol, gambling or drug addictions. For example I just saw @Thunder Bolt mentioned the fast 800 prescription for continuing to maintain weight as fasting at 5/2 on an ongoing basis, I tried that but had zero chance of maintaining it on a ongoing basis because of my relationship with food, I have a busy life, have ADHD, forget to eat, grab food on the run, I turn to food for comfort when I'm stressed and use it to bump my dopamine levels when I am tired and my motivation is low. The chance of me also sticking to a 5/2 fasting diet during periods like Christmas or holidays when the temptation to overeat is much higher is probably close to zero. I think some of the diet programmes offered by NHS are now catching on to this and provide behavioural and lifestyle support along with the usual advice on what and what not to eat.

 

[Harry Wilson's tackle]

There has been a glut of chat about these drugs on R5 today. The message seems to be these drugs are great for the obese with diabetes.

I won't be taking them. Yet.

 

[Weststander]

I didn't have time to read the whole thread so I missed that. For me the biggest problem is that a lot of the diet industry ignores the fact that for many people there is an emotional element to overeating and for some this can even develop in to a addiction as powerful and difficult to overcome as alcohol, gambling or drug addictions. For example I just saw @Thunder Bolt mentioned the fast 800 prescription for continuing to maintain weight as fasting at 5/2 on an ongoing basis, I tried that but had zero chance of maintaining it on a ongoing basis because of my relationship with food, I have a busy life, have ADHD, forget to eat, grab food on the run, I turn to food for comfort when I'm stressed and use it to bump my dopamine levels when I am tired and my motivation is low. The chance of me also sticking to a 5/2 fasting diet during periods like Christmas or holidays when the temptation to overeat is much higher is probably close to zero. I think some of the diet programmes offered by NHS are now catching on to this and provide behavioural and lifestyle support along with the usual advice on what and what not to eat.

I think of the 5:2 as a sustained initial effort to shed the bulk of the weight, something folk might start in January as an example. Not something that can be sustained over a lifetime, nor is it designed to be. It worked for Dr Mosley who started off in danger of an early death like his father, then for many of his readers.

Most people probably wouldn’t be willing to go through the anguish of an entire daytime with no food.

 

[Weststander]

There has been a glut of chat about these drugs on R5 today. The message seems to be these drugs are great for the obese with diabetes.

I won't be taking them. Yet.

Good article on the Tony Livesey show about 5:45pm today, the expert medic was clear they are safe.

The negative boiled down to some people would have side effects that wouldn’t wanr.