Hastings (and Rye) has not had a Liberal MP since 1906. It was Labour between 1997 and 2010, so they must be eyeing it up. Apart from that, it's been Tory since 1906.I doubt Lewes will return a Tory next time, and Hastings Cons have deselected their MP, so it might go back to Lib Dem.
Worthing's going to the interesting one. Labour could win both seats there - I think Loughton's definitely toast but Bottomley could be as well. I'm certain Lewes and Eastbourne will both go to Lib Dems and with Crawley goiing to Labour, Sussex could look very different