When we went to that very same villa, we flew to Bologna from Gatwick and hammered down the motorway and came inland from Ancona. It only took about 3 hours amd was quite cheap, and I think that was with BA.
Will check it out. The other concern with BA, which I meant to mention above, is the risk of a strike totally scuppering all our plans. Less of a risk out of LGW though it seems.