Muttiah Muralitharan has pulled out of Sri Lanka's tour of England because of an illness in his family.
The spinner will fly to Madras on Friday to be with his child and he is not expected to return.
A Sri Lanka team spokesman said: "At the moment we really don't know what the situation is. We hope to find out more on Friday."
Murali dominated the bowling attack as Sri Lanka earned a 1-1 draw in the Test series against England.
He had taken two wickets in the first two one-day matches, and was expected to play in the third ODI on Saturday.
The spinner will fly to Madras on Friday to be with his child and he is not expected to return.
A Sri Lanka team spokesman said: "At the moment we really don't know what the situation is. We hope to find out more on Friday."
Murali dominated the bowling attack as Sri Lanka earned a 1-1 draw in the Test series against England.
He had taken two wickets in the first two one-day matches, and was expected to play in the third ODI on Saturday.
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