Rotate to give some slightly more fringe players (e.g. Hemed / Baldock / Kayal / Krul) a bit of game time? Yeah, why not.
Massively weaken your team by dropping everyone? No. Only if we were playing either a top team (especially away) or a minnow we should beat with one arm tied behind our back.
Massively weaken your team by dropping everyone? No. Only if we were playing either a top team (especially away) or a minnow we should beat with one arm tied behind our back.