Birdie Boy
Well-known member
- Jun 17, 2011
- 4,253
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Main Coronavirus / Covid-19 Discussion Thread
- Thread starter GingerBeerMan
- Start date
beorhthelm
A. Virgo, Football Genius
- Jul 21, 2003
- 35,822
so you disgree with the premise that reception and year 1 are very important, or saying its bonkers for some other reason?
- Jul 10, 2003
- 27,346
Well all the action (or at least on the 3 best occasions) at today's government briefing came from the lectern to the left of Dom.
I wonder who was watching the 'right' lectern
Maybe we should have a separate thread of what happened at the all important Government briefing today and what it actually means ? Who is on for actually listening to what the government says and what it actually means ? I would imagine it's not many, because it's not in bold and outraged !
Much better (and certainly less complicated) to let someone else tell you what happened
I wonder who was watching the 'right' lectern
Maybe we should have a separate thread of what happened at the all important Government briefing today and what it actually means ? Who is on for actually listening to what the government says and what it actually means ? I would imagine it's not many, because it's not in bold and outraged !
Much better (and certainly less complicated) to let someone else tell you what happened
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I see that a US firm has taken the lead on the vaccine with some impressive results.
https://www.bbc.co.uk/news/health-52677203
Sadly, the Oxford vaccine that the Government were so proudly touting seems to be a non-goer.
https://www.bbc.co.uk/news/health-52677203
Sadly, the Oxford vaccine that the Government were so proudly touting seems to be a non-goer.
Well all the action (or at least on the 3 best occasions) at today's government briefing came from the lectern to the left of Dom.
I wonder who was watching the 'right' lectern
Maybe we should have a separate thread of what happened at the all important Government briefing today and what it actually means ? Who is on for actually listening to what the government says and what it actually means ? I would imagine it's not many, because it's not in bold and outraged !
Much better (and certainly less complicated) to let someone else tell you what happened
Didnt catch the briefing today. Could you sum it up
Jimmy Grimble
Well-known member
It’s bonkers because there is no need to make them the first year groups to go back. Formative years of learning are of course very important and so much of that is down to classroom environment and interactions. The learning at that age is predominantly through physical play and shared learning, which are not able to happen because of the social distancing guidelines. Imagine a risk assessment for a reception class during this and then consider if you think 4/5 olds can actually stick to it.
Start with the Primary years where more formal learning takes place and social distancing amongst other cleanliness standards can be realistically followed. Can’t see why they didn’t just opt for year 6 for the first week or two to see how it pans out.
Forgive me and please don’t think I’m judging you in the slightest, but what is your thinking behind your decision that it will be ok to send them in September and not in June ?
There’s no guarantee that this situation will be any better in September in fact I’d go as far as to say I think we’ll hit a plateau and there will be a fairly constant level of infection for the foreseeable future if not forever.
In September all school children could well be back at school instead of just three year groups, which would surely raise potential infection levels......or the schools could stay shut as the level had peaked again, thus leaving youngsters missing even more education.
I’ve genuinely been mulling this over whether to send my 11 year old, and I swing back and forth everyday, but I’m kind of leaning towards sending her back in June purely on the basis the slowly slowly restart may put her at less risk.
I’m lucky in the fact that she goes to a very small village school with only 7 kids in year 6, but it’s still weighing on my mind.
The only other spin on it is the data that’s shows kids are very low risk anyway but it’s certainly not an easy decision, she really wants to go back though so I’ll probably send her.
Blue Valkyrie
Not seen such Bravery!
I really meant September at the earliest.
If we get a bad 2nd Wave, then the schools will be shut again anyway.
I am pretty hopeful that the blood plasma treatments will have made significant progress by then. These aren't vaccines, but they will help fight the virus.
I think medical advances will be pretty quick, and outcomes a lot better reasonably soon.
My real concern is this nasty PIMS-TS syndrome that children can get from Coronavirus, and I also think this will be more understood in a few months time.
Just checked that. According to the torygraph the vaccone totally fained to work when tested in monkeys.
Remember, a vaccine is an attenuated pathogen (a sort of beaten up version that can't do harm, but is recognised as foreign). If it fails to trigger an immune response in monkeys it is unlikely to do any different in humans. That's a disappointment. And £47 million down the shitter.
Green Cross Code Man
Wunt be druv
That's weird, an article yesterday that I posted this morning from forbes, seemed to suggest the Oxford vaccine had partial success.
https://www.forbes.com/sites/willia...ord-covid-vaccine-work-in-monkeys-not-really/
Edit: Just read the Telegraph story and it seems to rehash some of that Forbes piece.
Albion Dan
Banned
It was successful in reducing the impact of the disease but not curing it. To be honest that may be as good as it ever gets.
Machiavelli
Well-known member
More twaddle. Ferguson doesn't make predictions, he models scenarios.
The Wizard
Well-known member
- Jul 2, 2009
- 18,398
Don’t like posting bad news, especially as it’s from the daily shitstain but doesn’t sound good for the oxford vaccine, all the monkeys given the vaccine contracted the virus, I’m not an expert but doesn’t sound like a particular success 
https://www.dailymail.co.uk/science...ine-does-not-stop-infection-experts-warn.html
https://www.dailymail.co.uk/science...ine-does-not-stop-infection-experts-warn.html
That's not what we want or need. Or expect. What is 'impact' anyway? In an animal study I look for the hardest end points - death and morbidity. Failing to prevent infection in a single animal is far from that.
As noted previously, making the first vaccine for a new virus is like inventing a new dish (let's call it 'curry'). Once you have cracked the key processes, you can then do seasonal embellishments. We are stil at the 'oh, I wonder if a bit of gunpowder might give it the heat we're looking for' stage I suspect.
beorhthelm
A. Virgo, Football Genius
- Jul 21, 2003
- 35,822
only half read the Forbes version and not the source, the Oxford team and Astrazeneca seem very sure of success to have gone to clinical trials and setting up production in anticipation.
ive read more throughly, seem the objection is the vaccine isnt an outright defeat of the virus but parital protection making it inconvinent, without the nasty effects on lungs. might that be sufficent?
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Indeed. I'll read the reports properly when they are published some place reliable.
If it is a fail....this is not remotely unusual. People slag off Big Pharma but the costs to get a new medicine proven are astronomical, and most fail - due to all sorts - difficulty making a deliverable (pill or injection), pharmacokinetics (metabolised too fast), lack of potency (maximum effect too weak), or efficacy (it simply doesn't do what was hoped), lack of selectivity (adverse effects)....with this the problem will be efficacy I expect.
Not unusual for a company to spunk £1000 million (or a billion in new speak) as still get a fail. After the first clinical efficacy trial most new drugs have to be put through massive multicentre trials and this is where the costs kick in - and the shortcomings emerge. We don't have time for that now so I expect to see a suboptimal vaccine go into widespread use early doors and prove less than lovely. We shall see. Part of the safety anxiety is due to this: https://en.wikipedia.org/wiki/Theralizumab
The reason this happened was the animal studies used human antibody that was destroyed by animals as 'foreign'. You need to test a monoclonal using the species variant (to test efficacy) then do safety testing in humans, starting from homeopathic dosages to find the no effect level. Anyway, talking shop now. A vaccine is not a monoclonal. The difference is like that between taking a horse to water, and throwing the horse in a river.
- Jul 10, 2003
- 27,346
If you really missed it and want to see it, here it is
If you want to fast forward 33.20, 35.30, 38.10 and 42.50 are all quite interesting. I wonder what a body language expert would have made of that
If you really missed it and want to see it, here it is
If you want to fast forward 33.20, 35.30, 38.10 and 42.50 are all quite interesting. I wonder what a body language expert would have made of that
30th february I remember it well
Albion Dan
Banned
And those scenarios predict outcomes that direct policy. The guy is hopeless and to boot flouted the rules that his own analysis imposed. How can you defend the guy?
Machiavelli
Well-known member
Because he's well respected by his peers. And if you were wise, you'd notice that there's a difference between plural and singular, which features in your first sentence. He'd be aware of the distinction.