Articles on CV

Blue Valkyrie said:

I'm taking Vit D supplements because of Covid-19 and fully believe that makes a difference - whether by the biochemical effect on the immune system, or by the placebo effect of that belief.

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CheeseRolls said:

What happens next ?

I think it is relatively easy to understand why you need a viable load of the virus to get infected. Just think about pregnancy versus a low sperm count, receiving a high dose obviously increases the chances, but that is where the analogy ends.

If this virus was totally unstoppable, it wouldn't matter if you got a little bit infected or a big bit infected, as the infection replicated it would just take slightly longer to take effect, when starting from a smaller base. We know this isn't true, yet the evidence is suggesting that receiving a higher does increases your chances not just of getting infected but also your chances of getting hit badly. What is that all about?

It looks like to me there are two groups here. An individual can be in one, none or both. Good host, someone who is especially good at letting the virus replicate and is therefore particularly good at spreading the virus. Weak defence, someone who is prone to getting seriously ill and more likely to end up in hospital and or die.

What are you supposed to do if you are old, fat, male, diabetic, black? or have one of a whole host of other high risk factors> I suspect that there is a cocktail of low risk drugs that won't stop you getting infected, but will reduce your chances of getting seriously ill. It looks like to me that Vitamin D supplements, are going to be central to this, but it may need a few more things as well, all of which is way beyond my basic understanding of chemistry and biology.

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Harry Wilson's tackle said:

I have read some papers and posted a recent summary study on the most favoured treatments (favoured by the eternally optimistic). The most compelling of all data is from the ONS (pasted below) that shows that risk of death from Covid is exquisitely related to age. Eyeball the yellow histogram and divide it by the blue histogram on the right to get the proportion of covid death per total number of people in that age group and you see that death risk goes through the roof after age 65. If we could treat age this would have the biggest effect on death risk. Failing that one assumes that staying fit and healthy in general terms offers survival benefit. Eat well, sleep well. And if over 60, try to isolate till we get a vaccine. That's the stark reality. For those younger the risk of death is so low it is little wonder people feel they should be allowed to 'get on with it'.

https://www.ons.gov.uk/peoplepopula...eredweeklyinenglandandwalesprovisional/latest

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CheeseRolls said:

Two metres or one: what is the evidence for physical distancing in covid-19?

https://www.bmj.com/content/370/bmj.m3223

Really like this one and will post the graphic on the main thread, as it works well as a stand alone.

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